Reports said Pochettino, who parted ways with English Premier League side Chelsea in May, would replace Gregg Berhalter as boss.
The 52-year old is being expected as the United States prepares to co-host the 2026 World Cup alongside Mexico and Canada.
He left Chelsea after finishing sixth in the Premier League in his only season in charge, after previous stints with Paris Saint-Germain and Tottenham.
Pochettino would be expected to take over the US squad in time for a friendly against Canada on September 7 at Kansas City.
