The Red Devils are looking to bounce back following a 1-1 draw at home to Burnley last weekend.
The result ended their hopes of playing Champions League football next season.
Ten Hag’s men are currently six points adrift of fifth-placed Tottenham in the race to qualify for the Europa League.
Despite a poor campaign for United, Fernandes has scored ten goals and provided seven assists in the league.
He could miss his second game of the season on Monday, having picked up a minor injury against Burnley.
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